Cuisines and cultures intermingle along the Mississippi, so you’re bound to taste something you love along the byway. Hotel Nauvoo’s famous buffet is laden with foods like grandma used to make. A visit to My Just Desserts means deciding between more of their famous, homemade half-pound chicken salad sandwich or saving room for their equally renowned tollhouse brownies and made from scratch pies. Head to Murphysboro, home to not one, but two award winning BBQ joints. Sink your teeth into a juicy burger, topped with bacon and cheese, sandwiched between two glazed donuts at Durty Gurt’s Burger Joynt. Indulge in a sweet treat at Lagomarcino’s where they’ve been dishing out homemade chocolates, candies, and ice cream for more than 100 years. Endlessly delicious options await along the Great River Road.