The Great River Road - Our Regions

Hotels, Motels & Resorts

Take your pick or try all three: boutique hotels, familiar chain brands, or a picturesque resort. Irish Cottage Boutique Hotel evokes the warmth and hospitality of the Emerald Isle with its authentic Irish pub, cozy gathering spaces, comfy rooms and Irish artwork. The Radisson on John Deere Commons offers the comfortable amenities of a chain hotel and a prime location near attractions and restaurants in downtown Moline. Outdoor thrill seekers will love a stay at Harpole’s Heartland Lodge, which features Illinois’ largest UTV/ATV course, a pistol range, sporting clays, horseback riding, and hunting excursions in prime whitetail country. From budget conscious options to luxurious resorts with all the amenities, the perfect place to lay your head is waiting along the byway.


Aerie's Resort

Americas Best Value Inn - Collinsville/St. Louis

AmericInn by Wyndham Fulton Clinton

AmericInn by Wyndham Moline Airport/Quad Cities

Bally's Quad Cities Casino & Hotel

Bel Aire Motel

Best Western Airport Inn

Best Western Chester Hotel

Best Western Galena Inn and Suites

Best Western Plus Parkway Hotel

Best Western Premier Alton

Chestnut Mountain Resort

Comfort Inn & Suites East Moline

Comfort Inn Alton

Comfort Inn Collinsville

Comfort Inn Edwardsville

Comfort Inn Moline-Quad Cities

Comfort Suites

Country Hearth Inn & Suites Edwardsville St. Louis

Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Galena, IL

Country Inn & Suites by Radisson, Moline Airport, IL

Davie School Inn

Days Inn by Wyndham Collinsville

DeSoto House Hotel

Doubletree by Hilton Hotel Collinsville - St. Louis

DraftKings at Casino Queen Hotel

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn St. Louis - Collinsville

Eagle Ridge Resort & Spa

Econo Lodge Inn & Suites

Econo Lodge Inn & Suites

Element Moline

Fairfield Inn & Suites Quincy

Fairfield Inn St. Louis Collinsville, IL

Four Points Hotel by Sheraton

Grant Hills Motel

Green Acres Motel

Hampton Inn & Suites Moline-Quad City International Airport

Hampton Inn & Suites St. Louis - Edwardsville

Hampton Inn & Suites St. Louis/Alton

Hampton Inn Collinsville

Hampton Inn St. Louis/Fairview Heights

Harpole's Heartland Lodge

Holiday Inn Express & Suites Edwardsville

Holiday Inn Rock Island-Quad Cities

Holiday Inn St. Louis-Fairview Heights


Hotel Nauvoo

Hyatt Place | Hyatt House East Moline/Quad Cities

Ice House Inn

Irish Cottage Inn & Suites

Knights Inn

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn by Wyndham Moline Airport

Lutes Bait & Escape

Marcotte's Family Motel

Microtel Inn & Suites

Monroe Street Suites

Motel 6 Moline, IL

Motel Nauvoo

Nauvoo Family Inn & Suites

Pere Marquette Lodge & Conference Center

Prairie Winds Motel

Quality Inn & Suites

Quality Inn & Suites

Quality Inn & Suites Moline-Quad Cities

Quality Inn Cairo I-57

Quality Inn East Dubuque

Quincy Inn & Suites

Radisson on John Deere Commons-Moline

Ramada by Wyndham Hotel and Day Spa

Red Bud Country Inn

Residence Inn Moline Quad Cities

Ruebel Hotel & Restaurant

Sandburr Run Golf Resort

Savanna Inn & Suites

Seven Eagles Resort & Campground

StageCoach Inn

Stoney Creek Hotel & Conference Center

Stoney Creek Inn

Stoney Creek Inn

Super 8 by Wyndham Alton

Super 8 by Wyndham Anna

Super 8 by Wyndham Collinsville St. Louis

Super 8 by Wyndham East Moline

Super 8 Motel by Wyndham Fairview Heights-St. Louis

Super 8 Motel by Wyndham Waterloo

The Atrium Hotel on Third

The Axis Hotel

The Bridgewater Inn

The Nest at Palisades Cabins

The View Motel

Town & Country Inn and Suites

TownePlace Suites St. Louis Edwardsville

Two Wheel Inn

William Watson Hotel

Woodruff Hotel